業績 (22)
Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population
Translational Psychiatry
Genome-wide Association Study of Subcortical Brain Structures in Japanese Ancestry: The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study
Research Square
Genetic risk, lifestyle adherence, and risk of developing hyperuricaemia in a Japanese population
Rheumatology (Oxford, England)
PMID: 39271169 ↗Deep-embedded clustering by relevant scales and genome-wide association study in autism
PloS one
PMID: 40440618 ↗Genetic effects on gestational diabetes mellitus and their interactions with environmental factors among Japanese women
Journal of human genetics
Effect of healthy lifestyle on renal dysfunction risk: interactions with genetic risk
Clinical kidney journal
Genome-wide association study of cognitive function in population-based cohorts in japan: The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study
Genes, brain, and behavior
PMID: 41108541 ↗Predictive value of the polygenic risk score for developing epilepsy: a systematic review and meta-analysis
Epilepsy & behavior: E&B
Associations of family history of hypertension, genetic, and lifestyle risks with incident hypertension
Hypertension Research
Association of circulating metabolites and polygenic risk score with incident type 2 diabetes: a prospective community-based cohort study
Cardiovascular diabetology
Preeclampsia prediction with maternal and paternal polygenic risk scores: the TMM BirThree Cohort Study
Scientific reports
Identification of risk loci for postpartum depression in a genome-wide association study
Psychiatry and clinical neurosciences
Genome-wide association study based on clustering by obesity-related variables uncovers a genetic architecture of obesity in the Japanese and the UK populations
Heliyon
PMID: 39247266 ↗Clustering by phenotype and genome-wide association study in autism
Translational psychiatry
Preeclampsia prediction with polygenic risk scores: the TMM BirThree Cohort Study
Prediction of Epilepsy Using Machine Learning on Integrated Polygenic Risk Scores and Perinatal Data: A Three-Generation Birth Cohort Study
日本人集団を対象とした大脳皮質の遺伝的構造の解明
ポリジェニックリスクスコアと周産期情報を用いた機械学習による熱性けいれん発症 予測
Prediction of Epilepsy Using Machine Learning on Integrated Polygenic Risk Scores and Perinatal Data: A Three-Generation Birth Cohort Study
日本人を対象としたつわりのゲノムワイド関連解析:三世代コホート調査
Genetic analysis of perinatal depression classified based on the depressive symptom trajectory
肥満関連要因を用いた肥満のクラスタリングとゲノムワイド関連解析による肥満の遺伝的構造の解明
ブログ記事 (4)
【論文後記】社会的孤立GWAS
臨床研究者のゲノム研究 ─ PRS QC解説
ポリジェニックリスクスコア(PRS)作成に必要なQC手順を、ベースデータ・ターゲットデータ別に解説。Nature Protocols 2020年のチュートリアルに準拠した実践的ガイドです。
臨床研究者のゲノム研究 ─ GWASの活かし方
GWASの基本から、ポリジェニックリスクスコア(PRS)やメンデリアンランダマイゼーション(MR)といった応用手法まで、臨床研究者がゲノム研究を活かすための実践的ガイドを解説します。
疾患リスク予測をどう生かすか ─ 疫学と予防医学の視点
疾患リスク予測はなぜ必要なのか?因果推論との違いを整理し、予測モデルが臨床・政策で意味を持つ3つの条件を疫学者の視点から考察するシリーズ第1回。