Research

研究紹介

Research Methods ● Perinatal Period ● GWAS ● Life's Essential 8 ● Social Isolation ● Tohoku Medical Megabank Organization ● Clustering Analysis ● Tohoku Medical Megabank Organization ● Obesity ● Systematic Review and Meta-Analysis ● Causal Inference ● Perinatal Period ● GWAS ● Science Communication ● Hyperuricaemia ● Risk Prediction ● Adverse Pregnancy Outcomes ● Urbanization and Health ● Literature Management ● Residential Greenness ● Obesity ● Genetic Epidemiology ● Causal Inference ● Announcement ● Gestational Diabetes Mellitus ● Polygenic Risk Score ● Clustering Analysis ● Autism Spectrum Disorder ● Gene-Environment Interaction ● Risk Prediction ● Breastfeeding ● Obesity ● Academic Writing ● Research Funding ● Preventive Medicine ● Mediation Analysis ● Preeclampsia ● Genetic Epidemiology ● Tohoku Medical Megabank Organization ● Heritability ● Polygenic Risk Score ● GWAS ● Clustering Analysis ● Gestational Diabetes Mellitus ● Edinburgh Postnatal Depression Scale ● Social Isolation ● Tohoku Medical Megabank Organization ● Perinatal Period ● Social Epidemiology ● Metabolomics ● Genetic Epidemiology ● Breastfeeding ● Cohort Study ● Lubben Social Network Scale ● Research Ethics ● Polygenic Risk Score ● Polygenic Risk Score ● Case-Control Study ● Autism Spectrum Disorder ● Preterm Birth ● GWAS ● Case-Control Study ● My Paper ● Preeclampsia ● Cognitive Function ● Genetic Epidemiology ● Preeclampsia ● Genetic Epidemiology ● Polygenic Risk Score ● Preeclampsia ● GWAS ● Atopic Dermatitis ● Placenta ● LDpred2 ● Risk Prediction ● Research Methods ● Postpartum Depression ● Blood Glucose ● Lipidomics ● Renal Function ● Risk Prediction ● Epilepsy ● Heritability ● Causal Inference ● Cardiovascular Health ● Normalized Difference Vegetation Index (NDVI) ● Perinatal Period ● Environmental Epidemiology ● Perinatal Period ● Mendelian Randomization ● Risk Prediction ● Type 2 Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Case-Control Study ● LD Score Regression ● Simons Simplex Collection ● Research Methods ● Perinatal Period ● GWAS ● Life's Essential 8 ● Social Isolation ● Tohoku Medical Megabank Organization ● Clustering Analysis ● Tohoku Medical Megabank Organization ● Obesity ● Systematic Review and Meta-Analysis ● Causal Inference ● Perinatal Period ● GWAS ● Science Communication ● Hyperuricaemia ● Risk Prediction ● Adverse Pregnancy Outcomes ● Urbanization and Health ● Literature Management ● Residential Greenness ● Obesity ● Genetic Epidemiology ● Causal Inference ● Announcement ● Gestational Diabetes Mellitus ● Polygenic Risk Score ● Clustering Analysis ● Autism Spectrum Disorder ● Gene-Environment Interaction ● Risk Prediction ● Breastfeeding ● Obesity ● Academic Writing ● Research Funding ● Preventive Medicine ● Mediation Analysis ● Preeclampsia ● Genetic Epidemiology ● Tohoku Medical Megabank Organization ● Heritability ● Polygenic Risk Score ● GWAS ● Clustering Analysis ● Gestational Diabetes Mellitus ● Edinburgh Postnatal Depression Scale ● Social Isolation ● Tohoku Medical Megabank Organization ● Perinatal Period ● Social Epidemiology ● Metabolomics ● Genetic Epidemiology ● Breastfeeding ● Cohort Study ● Lubben Social Network Scale ● Research Ethics ● Polygenic Risk Score ● Polygenic Risk Score ● Case-Control Study ● Autism Spectrum Disorder ● Preterm Birth ● GWAS ● Case-Control Study ● My Paper ● Preeclampsia ● Cognitive Function ● Genetic Epidemiology ● Preeclampsia ● Genetic Epidemiology ● Polygenic Risk Score ● Preeclampsia ● GWAS ● Atopic Dermatitis ● Placenta ● LDpred2 ● Risk Prediction ● Research Methods ● Postpartum Depression ● Blood Glucose ● Lipidomics ● Renal Function ● Risk Prediction ● Epilepsy ● Heritability ● Causal Inference ● Cardiovascular Health ● Normalized Difference Vegetation Index (NDVI) ● Perinatal Period ● Environmental Epidemiology ● Perinatal Period ● Mendelian Randomization ● Risk Prediction ● Type 2 Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Case-Control Study ● LD Score Regression ● Simons Simplex Collection ●

研究の基本姿勢

私たちの健康は、個人の遺伝・環境だけでなく、家族・地域社会・自然生態系との複雑なつながりの中で形成されています。EpiOrbisでは、大規模コホートデータとオミクスデータを組み合わせることで、このつながりを疫学的に解明することを目指しています。

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Theme 01

個別化健康アプローチ

大規模コホートデータとゲノム・エピゲノム・メタボロームなどのオミクス情報を統合し、健康状態がどのように個人ごとに異なる形で現れるかを解明します。

ポリジェニックリスクスコア（PRS）を用いた個別リスク評価や、バイオマーカーを活用した早期介入手法の開発を進めています。

詳細はこちら

Theme 02

母子・家族疫学

妊婦・子ども・家族全体を対象としたコホート研究を通じて、ライフコースにおける健康形成のメカニズムを探ります。

妊娠期の環境曝露が子どもの健康に与える影響や、家族内での健康の相互作用に着目しています。

詳細はこちら
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Theme 03

環境・生態系と健康

自然環境・生態系と人間の健康の関係を疫学的アプローチで解明します。グリーンスペースへのアクセス、大気・水・土壌汚染と健康アウトカムの関連を研究します。

プラネタリーヘルスの観点から、生態系の保全と人間の健康を統合的に捉える研究枠組みの構築を目指しています。

詳細はこちら