Research

研究紹介

Life's Essential 8 ● Tohoku Medical Megabank Organization ● Social Isolation ● Academic Writing ● Epilepsy ● Perinatal Period ● Science Communication ● Gestational Diabetes Mellitus ● Preeclampsia ● Hyperuricaemia ● Genetic Epidemiology ● Obesity ● LD Score Regression ● Social Epidemiology ● Causal Inference ● Gene-Environment Interaction ● Case-Control Study ● Systematic Review and Meta-Analysis ● Heritability ● Breastfeeding ● Case-Control Study ● Autism Spectrum Disorder ● Cardiovascular Health ● Preeclampsia ● Risk Prediction ● Preeclampsia ● Social Epidemiology ● Simons Simplex Collection ● Cognitive Function ● Literature Management ● Metabolomics ● Genetic Epidemiology ● Lubben Social Network Scale ● Heritability ● Research Methods ● Perinatal Period ● Perinatal Period ● Risk Prediction ● Perinatal Period ● Research Ethics ● GWAS ● Community-Based Cohort Study ● Lipidomics ● Causal Inference ● Science Communication ● Tohoku Medical Megabank Organization ● Renal Function ● Mendelian Randomization ● Breastfeeding ● GWAS ● Tohoku Medical Megabank Organization ● Polygenic Risk Score ● Preterm Birth ● Adverse Pregnancy Outcomes ● GWAS ● Clustering Analysis ● Tohoku Medical Megabank Organization ● Gestational Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Causal Inference ● Polygenic Risk Score ● Type 2 Diabetes Mellitus ● Polygenic Risk Score ● Research Funding ● Perinatal Period ● Mediation Analysis ● Clustering Analysis ● Obesity ● Polygenic Risk Score ● Social Isolation ● Edinburgh Postnatal Depression Scale ● Research Methods ● Risk Prediction ● Case-Control Study ● Genetic Epidemiology ● Risk Prediction ● Blood Glucose ● Announcement ● LDpred2 ● GWAS ● Postpartum Depression ● GWAS ● Genetic Epidemiology ● Obesity ● Risk Prediction ● Polygenic Risk Score ● Social Isolation ● Conference Participation ● Autism Spectrum Disorder ● Genetic Epidemiology ● Placenta ● Preeclampsia ● Clustering Analysis ● Life's Essential 8 ● Tohoku Medical Megabank Organization ● Social Isolation ● Academic Writing ● Epilepsy ● Perinatal Period ● Science Communication ● Gestational Diabetes Mellitus ● Preeclampsia ● Hyperuricaemia ● Genetic Epidemiology ● Obesity ● LD Score Regression ● Social Epidemiology ● Causal Inference ● Gene-Environment Interaction ● Case-Control Study ● Systematic Review and Meta-Analysis ● Heritability ● Breastfeeding ● Case-Control Study ● Autism Spectrum Disorder ● Cardiovascular Health ● Preeclampsia ● Risk Prediction ● Preeclampsia ● Social Epidemiology ● Simons Simplex Collection ● Cognitive Function ● Literature Management ● Metabolomics ● Genetic Epidemiology ● Lubben Social Network Scale ● Heritability ● Research Methods ● Perinatal Period ● Perinatal Period ● Risk Prediction ● Perinatal Period ● Research Ethics ● GWAS ● Community-Based Cohort Study ● Lipidomics ● Causal Inference ● Science Communication ● Tohoku Medical Megabank Organization ● Renal Function ● Mendelian Randomization ● Breastfeeding ● GWAS ● Tohoku Medical Megabank Organization ● Polygenic Risk Score ● Preterm Birth ● Adverse Pregnancy Outcomes ● GWAS ● Clustering Analysis ● Tohoku Medical Megabank Organization ● Gestational Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Causal Inference ● Polygenic Risk Score ● Type 2 Diabetes Mellitus ● Polygenic Risk Score ● Research Funding ● Perinatal Period ● Mediation Analysis ● Clustering Analysis ● Obesity ● Polygenic Risk Score ● Social Isolation ● Edinburgh Postnatal Depression Scale ● Research Methods ● Risk Prediction ● Case-Control Study ● Genetic Epidemiology ● Risk Prediction ● Blood Glucose ● Announcement ● LDpred2 ● GWAS ● Postpartum Depression ● GWAS ● Genetic Epidemiology ● Obesity ● Risk Prediction ● Polygenic Risk Score ● Social Isolation ● Conference Participation ● Autism Spectrum Disorder ● Genetic Epidemiology ● Placenta ● Preeclampsia ● Clustering Analysis ●

研究の基本姿勢

私たちの健康は、個人の遺伝・環境だけでなく、家族・地域社会・自然生態系との複雑なつながりの中で形成されています。EpiOrbisでは、大規模コホートデータとオミクスデータを組み合わせることで、このつながりを疫学的に解明することを目指しています。

Theme 01

個別化健康アプローチ

大規模コホートデータとゲノム・エピゲノム・メタボロームなどのオミクス情報を統合し、健康状態がどのように個人ごとに異なる形で現れるかを解明します。

ポリジェニックリスクスコア（PRS）を用いた個別リスク評価や、バイオマーカーを活用した早期介入手法の開発を進めています。

詳細はこちら

Theme 02

母子・家族疫学

妊婦・子ども・家族全体を対象としたコホート研究を通じて、ライフコースにおける健康形成のメカニズムを探ります。

妊娠期の環境曝露が子どもの健康に与える影響や、家族内での健康の相互作用に着目しています。

詳細はこちら

Theme 03

環境・生態系と健康

自然環境・生態系と人間の健康の関係を疫学的アプローチで解明します。グリーンスペースへのアクセス、大気・水・土壌汚染と健康アウトカムの関連を研究します。

プラネタリーヘルスの観点から、生態系の保全と人間の健康を統合的に捉える研究枠組みの構築を目指しています。

詳細はこちら