Research

研究紹介

GWAS ● Risk Prediction ● Preterm Birth ● Blood Glucose ● GWAS ● Epilepsy ● Obesity ● Preeclampsia ● Mediation Analysis ● Metabolomics ● Social Isolation ● Social Epidemiology ● Social Epidemiology ● Perinatal Period ● Community-Based Cohort Study ● Cardiovascular Health ● Heritability ● Tohoku Medical Megabank Organization ● Causal Inference ● Polygenic Risk Score ● Case-Control Study ● Genetic Epidemiology ● Announcement ● Polygenic Risk Score ● Causal Inference ● Risk Prediction ● Polygenic Risk Score ● Lipidomics ● Polygenic Risk Score ● Science Communication ● GWAS ● Adverse Pregnancy Outcomes ● Risk Prediction ● Research Methods ● Lubben Social Network Scale ● Genetic Epidemiology ● Genetic Epidemiology ● Case-Control Study ● Perinatal Period ● Preeclampsia ● GWAS ● Breastfeeding ● Genetic Epidemiology ● Clustering Analysis ● Perinatal Period ● Mendelian Randomization ● LDpred2 ● Hyperuricaemia ● Social Isolation ● Obesity ● Tohoku Medical Megabank Organization ● Research Methods ● Clustering Analysis ● Literature Management ● Edinburgh Postnatal Depression Scale ● Placenta ● Tohoku Medical Megabank Organization ● Tohoku Medical Megabank Organization ● Research Ethics ● Renal Function ● Gestational Diabetes Mellitus ● Life's Essential 8 ● Causal Inference ● Cognitive Function ● Conference Participation ● Systematic Review and Meta-Analysis ● Preeclampsia ● Heritability ● Breastfeeding ● Simons Simplex Collection ● Research Funding ● Autism Spectrum Disorder ● GWAS ● Case-Control Study ● Perinatal Period ● LD Score Regression ● Social Isolation ● Autism Spectrum Disorder ● Obesity ● Risk Prediction ● Risk Prediction ● Perinatal Period ● Preeclampsia ● Gestational Diabetes Mellitus ● Gene-Environment Interaction ● Clustering Analysis ● Polygenic Risk Score ● Genetic Epidemiology ● Science Communication ● Academic Writing ● Type 2 Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Postpartum Depression ● GWAS ● Risk Prediction ● Preterm Birth ● Blood Glucose ● GWAS ● Epilepsy ● Obesity ● Preeclampsia ● Mediation Analysis ● Metabolomics ● Social Isolation ● Social Epidemiology ● Social Epidemiology ● Perinatal Period ● Community-Based Cohort Study ● Cardiovascular Health ● Heritability ● Tohoku Medical Megabank Organization ● Causal Inference ● Polygenic Risk Score ● Case-Control Study ● Genetic Epidemiology ● Announcement ● Polygenic Risk Score ● Causal Inference ● Risk Prediction ● Polygenic Risk Score ● Lipidomics ● Polygenic Risk Score ● Science Communication ● GWAS ● Adverse Pregnancy Outcomes ● Risk Prediction ● Research Methods ● Lubben Social Network Scale ● Genetic Epidemiology ● Genetic Epidemiology ● Case-Control Study ● Perinatal Period ● Preeclampsia ● GWAS ● Breastfeeding ● Genetic Epidemiology ● Clustering Analysis ● Perinatal Period ● Mendelian Randomization ● LDpred2 ● Hyperuricaemia ● Social Isolation ● Obesity ● Tohoku Medical Megabank Organization ● Research Methods ● Clustering Analysis ● Literature Management ● Edinburgh Postnatal Depression Scale ● Placenta ● Tohoku Medical Megabank Organization ● Tohoku Medical Megabank Organization ● Research Ethics ● Renal Function ● Gestational Diabetes Mellitus ● Life's Essential 8 ● Causal Inference ● Cognitive Function ● Conference Participation ● Systematic Review and Meta-Analysis ● Preeclampsia ● Heritability ● Breastfeeding ● Simons Simplex Collection ● Research Funding ● Autism Spectrum Disorder ● GWAS ● Case-Control Study ● Perinatal Period ● LD Score Regression ● Social Isolation ● Autism Spectrum Disorder ● Obesity ● Risk Prediction ● Risk Prediction ● Perinatal Period ● Preeclampsia ● Gestational Diabetes Mellitus ● Gene-Environment Interaction ● Clustering Analysis ● Polygenic Risk Score ● Genetic Epidemiology ● Science Communication ● Academic Writing ● Type 2 Diabetes Mellitus ● Tohoku Medical Megabank Organization ● Postpartum Depression ●

研究の基本姿勢

私たちの健康は、個人の遺伝・環境だけでなく、家族・地域社会・自然生態系との複雑なつながりの中で形成されています。EpiOrbisでは、大規模コホートデータとオミクスデータを組み合わせることで、このつながりを疫学的に解明することを目指しています。

Theme 01

個別化健康アプローチ

大規模コホートデータとゲノム・エピゲノム・メタボロームなどのオミクス情報を統合し、健康状態がどのように個人ごとに異なる形で現れるかを解明します。

ポリジェニックリスクスコア（PRS）を用いた個別リスク評価や、バイオマーカーを活用した早期介入手法の開発を進めています。

詳細はこちら

Theme 02

母子・家族疫学

妊婦・子ども・家族全体を対象としたコホート研究を通じて、ライフコースにおける健康形成のメカニズムを探ります。

妊娠期の環境曝露が子どもの健康に与える影響や、家族内での健康の相互作用に着目しています。

詳細はこちら

Theme 03

環境・生態系と健康

自然環境・生態系と人間の健康の関係を疫学的アプローチで解明します。グリーンスペースへのアクセス、大気・水・土壌汚染と健康アウトカムの関連を研究します。

プラネタリーヘルスの観点から、生態系の保全と人間の健康を統合的に捉える研究枠組みの構築を目指しています。

詳細はこちら